形气神相失致瘤的生物学机制及中医药防治策略探讨

关键词：形；气；神；恶性肿瘤；神经调控；能量代谢；中医药；防治策略

中图分类号：R273 文献标志码：A 文章编号：1007-3213（2025）08-2058-07

DOI：10.13359/j.cnki. gzxbtcm.2025.08.034

Abstract： The life view of physique- qi -spirittrinity is the core theory for explaining the physiological activities of human body and the evolution of disease pathology in traditional Chinese medicine（TCM），and willbring about an overview of TCM tumorigenesis.This paper explores the biological basis of tumor from the perspective of disorders of physique，qi and spirit：there is a correlation between qi -physique transformation and energy and substance metabolism，and between spirit-emotion and neuromodulation；the nerve-metabolism pathway contributes to partial biological basis of tumor from the perspective of disordersof physique，qi and spirit. Furthermore，it puts forward the strategies for preventionand treatment with TCM through thesimultaneous regulation of physique，qiand spirit：eliminating the mass to inhibit the tumor，and improving physique to preserve life in the view of treating physique；replenishing qi to strengthen the body，and ventilating qi to remove toxins in the view of treating qi ；regulating the spirit to treat cancer through comprehensive therapy in the view of treating spirit.Theexplorationonthe biological basis of tumor from the perspectiveof disordersof physique，qi and spirit will further embody the unique advantages of TCM theories in understanding malignant tumors，and will provide useful references for the model of synergistic prevention and treatment of malignant tumors with TCM.

Keywords：physique；qi；spirit；malignant tumors；neuromodulation；energy metabolism；traditional Chinese medicine； prevention and control strategy

全球范围内，恶性肿瘤已成为除传染性疾病外的第二大死亡原因，每年约1000万人死于恶性肿瘤，恶性肿瘤已成为严重威胁民众健康安全的重大公共卫生问题。（剩余12347字）