肠道菌群代谢产物对阿霉素诱导的心脏毒性的抑制作用

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【Abstract】Doxorubicinhasachievedremarkableresultsinthefieldoftumortreatment，butitsclinicalapplicationishnderedby cardiactoxicitymainlymanifestedinheartfailure.Studieshaveshothattheintestinalflorametabolitesandthecardiovasularste interactwithachterndaniibitadotoicitytoughhasmssuchstioidatandntiiflamtio.Thrrtfosisn discuingesigificaneofitestialfloametabolitesndterositieimpactooxorbicinardotoxicityeiistoproidew strategyforthepreventionandtreatmentofdoxorubicin-inducedcardiotoxicityfromtheperspectiveof intestialflorametabolites.

【Keywords】 Doxorubicin;Cardiotoxicity;Metabolites of intestinal flora

阿霉素是临床上治疗乳腺癌、肺癌、淋巴瘤和急性白血病常用的化疗药物[1]。（剩余12938字）