膝关节骨性关节炎患者神经病理性疼痛发生的危险因素分析

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[中图分类号] R684.3;R441.1 [文献标志码] A

Risk factors for neuropathic pain in patients with knee osteoarthritisZHANG Yijing， ZHOU Xinjie， WANG Lei，FAN Kaiyong，LI Tieshan（Qindao Medical College of Qingdao University， Qingdao 266071，China）

[ABSTRACT]ObjectiveTo investigate theonset of neuropathic pain（NP）inpatients with kneeosteoarthritis（KOA）and relatedinfluencingfactors.MethodsAtotalof313KOApatientswhoattendedtheoutpatientserviceofDepartmentofRehabilitationMedicineinourhospitalfromJuly223toOctober2024wereenroled，andacordingtothescoringresultsofthePainDETECTquestionnaire，theywere divided into NP groupand non-NP group.The two groups werecompared in terms ofage，sex， body mass index （BMI），durationof kneepain symptoms，Kelgren-Lawrence （K-L）grading，pain VisualAnalogue Scale（VAS） score，WesternOntarioand McMaster UniversitiesOsteoarthritis Index（WOMAC），Hospital AnxietyandDepresion Scale （HADS）score，and knemagnetic resonance imaging（MRI）findings.Alogisticregresionanalysis was performed forthe indicatorswithstatisticalsignificanceidentifdbytheunivariateanalysistoobtaintheriskfactorsforNP.ResultsOfallatients， the patients with NP accounted for 16.61% . There were significant differences between the two groups in age，sex，pain VAS score，WOMAC，HADS score，andthe proportionofpatients with meniscusinjury，softtisue edemaaroundthe kneejointor knee joint ligament injury on MRI （ Y=16.272-49.953，χ2=12.897-23.792，P<0.05） . The logistic regression analysis showed that oldage，ahighpain VASscore，ahigh HADSscore，thepresenceof softtisseedema aroundthe kneejoint，andthepresence of knee joint ligament injury were risk factors for the onset of NP （ ΔP<0.05Δ ．ConclusionOld age，a high pain VAS score，a high HADS score，the presenceofsoft issueedema aroundthe kneejoint，andthe presenceofknee joint ligamentinjuryarerisk factors for the onset of NP in KOA patients.

[KEYWORDs]Osteoarthritis，knee；Pain；Neuralgia；Pain management；Risk factors

骨性关节炎（OA）是全球范围内，尤其是中老年人群中最常见的关节炎，表现为关节疼痛和关节功能受损[1]。（剩余6859字）