运动康复改善冠状动脉微循环障碍的相关机制研究进展

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【关键词】冠状动脉微循环障碍；运动康复；内皮功能障碍；线粒体自噬；血管周围脂肪组织【中图分类号】R331.37【文献标识码】A DOI：10.12114/j.issn.1007-9572.2024.0286

【Abstract】Coronary microcirculation disorder refers to the clinical syndrome caused by the abnormal structure and/ orfunctionoftheprecoronaryrteriolesandarterioles，whichiscloselyrelatedtotheprognosisofcardiovasculardiseasessuch asacutecoronarysyndrome，coronaryofender vascularrevascularizationand heartfailure.Asanon-drug intervention for the preventionandtreatmentofcardiovasculardiseases，exerciserehabilitation improves endothelial functionandoxidative inflammationstimulationinpatients withcoronarymicrocirculationdisorders trough signaling molecules，restores mitochondrial autophagylevel，and induces functionalrecoveryofperivascularadiposetissue.Thisarticlereviewedtheresearch progresof exerciseehabilitationinterventionincoronarymicrocirculationdisorder，aimingtoprovidemoreideasandreferencesforexercise rehabilitation treatment of coronary microcirculation disorder.

【Key words】Coronary microcirculationdisorder；Sports rehabilitation；Endothelial dysfunction；Mitochondrial autophagy；Perivascular adipose tissue

随着冠状动脉造影（CAG）、核素灌注等影像技术的普及，冠状动脉微循环障碍（coronarymicrocirculationdisorder，CMD）检出率逐渐上升。（剩余21956字）