肌肉超声对重症监护室获得性衰弱早期预测的Meta分析

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Muscle ultrasound for early prediction for acquired weakness in intensive care unit：a Meta-analysis

HE Mei，ZHANG Li，JIN Zhenghui，YE Yan，LIU Miao，LIU Surong

School of Nursing，Chengdu University of Traditional Chinese Medicine，Sichuan 610075 China

Corresponding Author  LIU Surong，E-mail：Liusurong2004@163.com

Abstract Objective：To assess the prediction value of muscle ultrasound for acquired weakness in intensive care unit（ICU-AW） by Meta-analysis，and to provide a basis for clinical diagnosis.Methods：PubMed，EMbase，the Cochrane Library，Web of Science，CNKI，CMB，VIP，and WanFang Database were searched，and the retrieval time was from the inception to March 1，2024.The literature was screened according to the inclusion and exclusion criteria，and the related diagnostic test category of muscle ultrasound for ICU-AW was included in the study.The quality assessment of diagnostic accuracy studise（QUADAS-2） was used to evaluate the quality of the included literature.Results：A total of 11 articles were included，including 587 critically ill patients.Meta-analysis results showed that the combined sensitivity，combined specificity，combined positive likelihood ratio，combined negative likelihood ratio，and combined diagnostic ratio of muscle ultrasound in the diagnosis of ICU-AW was 0.71（95%CI 0.60-0.80），0.78（95%CI 0.74-0.81），3.15（95%CI 2.72-3.66），0.38（95%CI 0.27-0.52） and 8.33（95%CI 5.41-12.83），respectively.The area under the curve value for the combined subject work characteristics was 0.80（95%CI 0.76-0.83）.Conclusion：Current evidence shows that muscle ultrasound has good prediction value for early ICU-AW and may provide a reference for clinical diagnosis of ICU-AW.

Keywords  muscle ultrasound; aquired weakness in intensive care unit; early prediction; Meta-analysis; evidence-based nursing

摘要  目的：通过Meta分析评估肌肉超声对重症监护室获得性衰弱（ICU⁃AW）的早期预测价值，为临床诊断提供依据。（剩余8586字）