西安市农村地区17年痴呆流行变化

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中图分类号：R749.16 文献标志码：ADOI：10.7652/jdyxb202505002

Trends of prevalence and mortality of dementia over 17 years in rural areas of Xi'an City

HUO Kang1，SHANG Suhang1，DANG Liangjun1，GAO Ling1，WEI Shan1， WANG Jin1，CHEN Chen1，ZENG Lingxia²，QU Qiumin1 （1. Department of Neurology，The First Afiliated Hospital of Xi'an Jiaotong University， Xi'an 7loo6l；2. Department of Epidemiology and Health Statistics，School of Public Health，Xi'an Jiaotong University Health Science Center，Xi'an 7loo61，China）

ABSTRACT：ObjectiveBy comparing the prevalence and mortality of dementia among rural people in Xi'an in 1997 and 2O14 to clarify the epidemiological changes of dementia among rural people in the city over l7 years. Methods In 1997 and 20l4，people aged 55 and above in villages in Xi‘an were selected by random cluster sampling method，and face-to-face questionnaire survey was conducted by combining centralized and home visits. Dementia and its subtypes were diagnosed by“the thre-step method”；the changes of dementia prevalence and mortality were compared between the two surveys.ResultsThe prevalence of dementia among rural residents aged 55 and above in Xi'an was 3.49% in 1997，with age-gender standardized prevalence of 2.08% .In 2014，the prevalence of dementia was 4.25% ，with age-gender standardized prevalence of 2.78% .Over the 17 years，the prevalence of dementia increased by 1.79 times （ OR=1.79 ， 95% （204号 CI 1.20-2.65 ， P=0.004： ，witha1.9-fold increase in femalesand al.67-fold increase in males.The mortality of dementia patients was 61.76‰ and age-gender standardized mortality was 60.20‰ in 1997，while the mortality was 35.71‰ and age-gender standardized mortality was 34.18% in 2014.The mortality of dementia decreased by 33% over the 17 years ⋅HR=0.33 ， 95%CI： 0.15- 0.74， P=0.007 .Conclusion The prevalence of dementia in rural areas of Xi'an increased significantly over the 17 years，but the mortality rate decreased，and this trend was more obvious in women.

KEY WORDS：dementia；prevalence；mortality；rural population；epidemiology

伴随我国人口老龄化的快速进展，痴呆已成为严峻的健康问题和社会问题。（剩余9931字）