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颈源性失眠发病机制研究进展

摘 要 颈源性失眠的发病率逐年升高并成为临床治疗热点,本文通过检索并梳理近年相关文献,从下丘脑-垂体-肾上腺轴失调、脑神经递质、阿片能信号通路、促炎细胞因子、运动节段囊状韧带受压、肌筋膜触发点、社会环境和遗传因素等七个方面论述颈源性失眠的发病机制,为后续临床诊治进一步研究提供指导。

关键词 颈源性失眠;发病机制;研究进展

中图分类号:R749 文献标志码:A 文章编号:1006-1533(2023)22-0038-03

引用本文 冯蕾, 蔡之幸, 刘帅, 等. 颈源性失眠发病机制研究进展[J]. 上海医药, 2023, 44(22): 38-40; 57.

基金项目:上海市闵行区卫生健康委员会科研课题(2021MW42)

Research progress in the pathogenesis of cervical insomnia

FENG Lei1, CAI Zhixing2, LIU Shuai1, LI Fei1, ZHU Danyang2

(1. Department of Traditional Chinese Medicine of Huacao Community Health Service Center of Minhang District, Shanghai 201107, China; 2. Department of Traditional Chinese Medicine of Tongren Hospital of School of Medicine Affiliated to Shanghai Jiao Tong University, Shanghai 200336, China)

ABSTRACT The incidence of cervical insomnia is increasing year by year and has become a hot spot in clinical treatment, this article retrieved and summarized the pathogenesis of cervicogenic insomnia in relevant literatures in recent years from seven aspects, including hypothalamic-pituitary-adrenal axis dysfunction, brain neurotransmitters, opioid signal pathway, proinflammatory cytokines, compression of motor segment cystic ligament, myofascial trigger points, social environment and genetic factors, and provides guidance for further clinical diagnosis and treatment.

KEY WORDS cervical insomnia; pathogenesis; research progress

颈源性失眠主要因颈椎退行性变、外伤或颈部肌肉劳损引起颈部关节疼痛、椎动脉供血不足及不同程度植物神经功能紊乱而导致的入睡困难、早醒、睡眠时间短、睡眠质量差等症状[1]。(剩余8579字)

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