重组人干扰素α-2b治疗小儿水痘的临床效果观察

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摘 要 目的:分析小儿水痘临床治疗中重组人干扰素α-2b的临床效果。方法:以奇偶数列法为标准,将92例水痘患儿分为对照组和观察组,各46例。在对症支持治疗的基础上,对照组予以阿昔洛韦片治疗,观察组予以重组人干扰素α-2b治疗,比较临床效果差异。结果:观察组临床治疗效果优于对照组;全部脱痂自愈时间、水疱结痂时间、退热时间、瘙痒缓解时间均短于对照组(P
关键词 重组人干扰素α-2b 小儿水痘 疱疹 发热
中图分类号:R979.5; R725.1 文献标志码:A 文章编号:1006-1533(2023)09-0038-03
引用本文 朱一民, 黄淑萍, 张丹成. 重组人干扰素α-2b治疗小儿水痘的临床效果观察[J]. 上海医药, 2023, 44(9): 38-40; 66.
Clinical efficacy of recombinant human interferon α-2b in the treatment of children with chickenpox
ZHU Yimin, HUANG Shuping, ZHANG Dancheng
(Department of Pediatrics, Jiujiang Maternal and Child Health Hospital, Jiujiang 332000, China)
ABSTRACT Objective: To analyze the clinical efficacy of recombinant human interferon a-2b in the treatment of children with chickenpox. Methods: Using the odd-even series method, ninety -two children with chickenpox were divided into a control group and an observation group with 46 cases each. On the basis of symptomatic supportive treatment, the control group was treated with acyclovir tablets, while the observation group was treated with recombinant human interferon a-2b. The clinical efficacy was compared between the two groups. Results: The clinical efficacy was better and the times for self-healing, blisters crusting, fever reduction and itching relief were shorter in the observation group than the control group (P
KEY WORDS recombinant human interferon a-2b; varicella in children; herpes; fever
水痘是小儿群体中的一种多发病症,患儿的临床表现包括发热、疱疹等,这些临床特点不仅会对患儿造成巨大的身心痛苦,如果患儿没有得到及时有效的诊治可对其正常生长发育造成严重影响,而且水痘还具有传染性[1-2]。(剩余4800字)