胎盘代谢组学方法在异常妊娠研究中的应用

［摘要］ 异常妊娠与胎盘功能失调密切相关，通过胎盘代谢组学分析，可以了解异常妊娠的特有代谢紊乱和病理机制。本文对胎盘代谢组学在各类异常妊娠中的应用成果进行综述，并对其现状及前景进行讨论。

［关键词］ 胎盘；代谢组学；妊娠并发症；新生儿；综述

［中图分类号］ R714.56;R722.1

［文献标志码］ A

［文章编号］ 2096-5532（2024）06-0941-04

doi：10.11712/jms.2096-5532.2024.60.195

［开放科学（资源服务）标识码（OSID）］

［网络出版］ https：//link.cnki.net/urlid/37.1517.R.20250107.1910.005;2025-01-08 13：52：56

The application of placental metabolomics in abnormal pregnancies

ZHANG Fanzhen， LIU Qiang， ZHANG Haixia

（School of Clinical Medicine， Weifang Medical University， Weifang 26105  China）

［Abstract］ Abnormal pregnancies are closely associated with placental dysfunction， and placental metabolomics can help to understand the unique metabolic disruptions and pathological mechanisms in abnormal pregnancies. This article reviews the application of placental metabolomics in various types of abnormal pregnancies and discusses its current status and future prospects.

［Key words］ placenta; metabolomics; pregnancy complications; infant， newborn; review

受到基因和环境的共同影响，我国异常妊娠的发生率超过5%[1]。（剩余12730字）