植物可变剪接研究进展

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摘要:选择性剪接广泛存在于植物中,是生物体转录组和蛋白质组多样性的主要来源。随着科技的发展,可变剪接的研究方法逐渐变得简单方便高效,越来越多的可变剪接事件在植物中被发现。本研究对植物可变剪接的机制、研究方法以及几种植物的最新可变剪接研究进展进行分析,并且对未来应深入研究的方向给出了建议。
关键词:mRNA;可变剪接;植物;拟南芥;大豆;单分子测序技术
中图分类号:S1文献标志码:A论文编号:cjas2020-0190
Research Progress of Alternative Splicing in Plants
XU Yue1,2,3,4, WANG Xi1,2,3, SHEN Zimeng1,2,3,5
(1College of Advanced Agriculture and Ecological Environment of Heilongjiang University/ Sugar Beet Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150080, Heilongjiang, China; 2The Key Laboratory of Sugar Beet Genetic Breeding, Colleges of Heilongjiang Province/ Sugar Beet Engineering Research Center of Heilongjiang Province, Harbin 150080, Heilongjiang, China; 3National Sugar Crops Improvement Center/Key Laboratory of North Sugar Crop Resource and Utilization, Chinese Academy of Agricultural Sciences, Harbin 150080, Heilongjiang, China; 4Shanghai Belief Biomed Pharmaceutical Technology Co., Ltd., Shanghai 200000, China; 5China Blue Sky Ecological Technology (Beijing) Co., Ltd., Beijing 100083, China)
Abstract: Alternative splicing is widespread in plants and is the main source of transcriptome and proteome diversity in organisms. With the development of science and technology, the research methods of alternative splicing have gradually become simple, convenient and efficient, and more and more alternative splicing events have been discovered in plants. The article mainly introduces the mechanism and research methods of alternative splicing in plants, as well as the latest research progress of alternative splicing in several plants, and puts forward suggestions on the research direction in the future.
Keywords: mRNA; alternative splicing; plant; Arabidopsis; soybean; single molecule sequencing technology
0引言
可变剪接又称选择性剪接(Alternative Splicing, AS),指在一个mRNA前体中通过不同的剪接方式产生不同的mRNA异构体的过程。(剩余10791字)