多巴胺在治疗感染性休克患者中的应用

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【摘要】目的：分析多巴胺对感染性休克的治疗效果。方法：纳入68例感染性休克患者，2020年6月—2022年6月就诊，对所有患者行回顾性研究，根据治疗方式分组，对照组患者34例，接受常规治疗，观察组34例联合使用多巴胺，对比治疗前后休克指数、生化指标、肾功能水平。 结果：患者治疗前休克指数、生化指标、肾功能水平对比无差异（P>0.05），观察组治疗后休克指数、乳酸、心率、尿素氮水平低于对照组，平均动脉压、中心静脉压、内生肌酐清除率和每小时尿量高于对照组，组间对比有差异（P

【关键词】多巴胺；感染性休克；休克指数；生化指标；肾功能

Application of dopamine in the treatment of septic shock patients

CHEN Caihong1，2

1.Pingchuan District People’s Hospital of Baiyin City， Gansu Province， Baiyin， Gansu 730913， China 2.Tantian Township Health Center， Pingchuan District， Baiyin City， Gansu Province， Baiyin， Gansu 730913， China

【Abstract】Objective：To analyze the therapeutic effect of dopamine on septic shock. Methods：A total of 68 patients with septic shock were included and treated from June 2020 to June 2022. A retrospective study was performed on all patients， who were divided according to treatment. 34 patients in the control group received conventional treatment， and 34 patients in the observation group received combined dopamine. The shock index， biochemical indexes and renal function levels before and after treatment were compared. Results：There were no differences in shock index， biochemical index and renal function before treatment（P>0.05）. After treatment， the shock index， lactic acid， heart rate and urea nitrogen level in observation group were lower than those in control group， while the mean arterial pressure， central venous pressure， endogenous creatinine clearance and urine volume per hour in observation group were higher than those in control group， and there were differences between groups （P

【Key Words】Dopamine； Septic shock； Shock index； Biochemical index； Renal function

感染性休克即為脓毒性休克，由微生物及其产物所致，感染灶中微生物及其产物入侵血液循环，激活宿主各种系统，释放细胞因子和介质，在身体器官和系统上发挥作用，影响其灌注，导致代谢紊乱、功能障碍，甚至发展成为多器官功能衰竭，即为感染性休克[1]。（剩余3541字）