变异链球菌与口腔致龋微生物相互作用的研究进展

［摘要］随着人口老龄化速度的加快，老年人患龋情况日益严峻。变异链球菌是主要致龋菌，乳杆菌和血链球菌等也参与了龋病的发生发展，而戈登链球菌可以抑制龋病。本文就变异链球菌与上述口腔微生物相互作用作一综述，为老年龋病防治提供新思路。

［关键词］龋病；变异链球菌；血链球菌；戈登链球菌

doi：10.3969/j.issn.1674-7593.2024.02.023

Recent Advances in Research on Interactions between Streptococcus Mutansand Oral Cariogenic Microorganisms

Gao Wenjia，Xie Yuandong，Li Chunwang，Wang Yawen，Yuan Meng，Li Yi**

Hospital of Stomatology，Jilin University，Changchun130021

**Corresponding author：Li Yi，email：lyi99@jlu.edu.cn

［Abstract］As the global population ages at an accelerated pace，the prevalence of dental caries among the elderly is escalating，presenting a growing health concern.Streptococcus mutans is widely acknowledged as the primary cariogenic bacteria，while Lactobacillus and Streptococcus sanguinis also play significant roles in the initiation and progression of dental caries.In contrast，Streptococcus gordonii demonstrates an inhibitory effect on dental caries.This article meticulously reviews the intricate interactions among Streptococcus mutans，Lactobacillus，Streptococcus sanguinis，and Streptococcus gordonii in the oral microbiome.By delving into these microbial dynamics，it offers novel perspectives for the prevention and treatment of dental caries among the elderly.These insights contribute to the development of innovative strategies aimed at addressing the complexities of dental caries in the context of an aging population.

［Key words］Dental caries;Streptococcus mutans;Streptococcus sanguinis;Streptococcus gordonii

与其他年龄组相比，老年人患口腔疾病的风险更高，全球几乎一半的老年人患有未经治疗的龋齿，龋病会导致其牙齿脱落和咀嚼困难。（剩余11352字）