用于即时检验的微流控纸基分析设备的研究进展

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Abstract： Point-of-care testing （POCT） refers to a category of diagnostic tests that are performed at or near to the site of the patients （also called bedside testing） and is capable of obtaining accurate results in a short time by using portable diagnostic devices， avoiding sending samples to the medical laboratories. It has been extensively explored for diagnosing and monitoring patients’ diseases and health conditions with the assistance of development in biochemistry and microfluidics. Microfluidic paper-based analytical devices （µPADs） have gained dramatic popularity in POCT because of their simplicity， user-friendly， fast and accurate result reading and low cost. Several µPADs have been successfully commercialized and received excellent feedback during the past several decades. This review briefly discusses the main types of µPADs， preparation methods and their detection principles， followed by a few representative examples. The future perspectives of the development in µPADs are also provided.

Key words： point-of-care testing; microfluidic paper-based analytical devices; sensor; personalized medical treatment; portable diagnostic equipment

CLC number： TP212                     Document code： A DOI： 10.3969/j.issn.1007-7146.2025.01.001

摘 要：即时检验（POCT）是指在患者现场或附近进行的一类诊断测试（也称为床边测试），能够通过使用便携式诊断设备在短时间内获得准确的结果，避免将样本送往医学实验室。（剩余38669字）