膀胱肿瘤整块切除术手术技术与病理评估的研究进展

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Research progress on en bloc resection of bladder tumor： surgical techniques and pathological assessment

HAO Zihan，JIANG Ning，YANG Rong，GUO Hongqian

（Department of Urology，Nanjing Drum Tower Hospital，the Afiliated Hospital of Nanjing University

Medical School，Nanjing 210008，China）

ABSTRACT：En bloc resectionof bladder tumor（ERBT），asaninnovative procedure forconventional transurethralresection of bladder tumor（cTURBT），has become an important treatment option for non-muscle invasive bladdercancer（NMIBC）. AlthoughERBThas beenrecommended byinternational guidelines，itstechnical standardization，verificationof long-term survival benefitsandstratificationof indicationsarestillthefocusoffutureresearch.Thisarticlefistprovidesanoverviewof the surgical techniquesofERBT，and then elaboratesontheadvantages anddisadvantagesofthethreeenergysourcesof ERBT， namely，electrocauteryasendHybidknife.Iersofpathologicalsessment，urrentesearchsuggeststattectio of detrusor muscle in surgicalspecimens canreflect thequalityof the surgery.The integrityof pathological specimes and diagnosticconsistency have promoted the progressof sub-staging of Tlbladercancer and havealsodriven more research on microscopic indicatorsrelated toprognosis.Finally，this articlereviews whetherrepeated transurethralresectioncanbeavoided to help optimize individualized treatment for bladder tumor.

KEYWORDS：en blocresectionof bladder tumor；transurethralresectionof bladder tumor；bladdercancer；surgical techniques； pathology

中图分类号：R737.14 文献标志码：A DOI：10.3969/j.issn.1009-8291. 2025. 08. 014

膀胱癌在全球范围内的发病率位居第9位，在男性群体中是第6常见的恶性肿瘤[1]。（剩余20085字）