鼻烟窝桡动脉阻力指数在重症超声指导脓毒性休克患儿液体复苏治疗中的临床价值

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Clinical value of snuff box radial artery resistance index for guiding fluid resuscitation in septic shock children by critical care ultrasound

CHENYuanhao,CAOMi,CHENHanbin

ABSTRACTObjectiveTo explore the clinical value of snuffbox radial artery resistance index(SBRI）for guiding fluidresuscitation insepticshockchildrenbycriticalcareultrasound.MethodsAtotalof8septicshock childrenadmitted toourhospital wereselectedandrandomlydividedintoacontrol group（using criticalultrasound toguide hemodynamic management andfluidresuscitation）andanobservation group(using critical ultrasound combinedwith simultaneous SBRI monitoring togudehemodynamicmanagementandfluidresuscitation）,with4Ocasesineachgroup.Thefluidintakeand positivefluidbalanceat1hafterfluidresuscitation,thenegativefluidbalanceandmechanicalventilationdurationat12hafter fluidresusiatio,ctateeaanetsat24d48teuiatiosellftiulstolic (LVEDV）,left ventricular end-systolic volume(LVESV）,maximum inferior vena cava diameter( IVCmax ),left ventricular outflow tract elocity-time integral(VTI),andSBRIat1hand12hafterresuscitationwerecompared between two groups.The28-day mortalitybetwenthetwo groups wascompared.ResultsTheobservation group exhibited significantly greaterfluidintake after 1hfluidresuscitationandalargerpositivefluid balancecompared tothecontrolgroup，withstatiticallsignificant differences（both Pmax and VTI were greater than those at 1hafterfluidresuscitation,whileLVEDVandLVESVweresmalerthanthoseat1hafterfluidresuscitation,withstatisticaly significant differences(all P max and VTI were greater than those in the control group，and LVEDV and LVESV were smaller than those in the control group，with statistically significant differences（all P

KEYWORDSUltrasonography;Resistanceindex,snuffbotleradialartery;Septicshock;Fuidresuscitation;Childr

脓毒症是由感染引发的全身性炎症反应综合征，其病理机制为宿主免疫调节机制失调，导致多器官灌注不足和功能障碍，具有较高的死亡率[1]。（剩余12100字）