维生素D在溃疡性结肠炎中的应用进展

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AbstractUlcerativecolitis （UC）isachronic，recurent intestinal inflammatorydisorder.Inrecentyears，theroleof vitaminDinthetreatmentofUChasatractedwidespreadattention.StudieshavedemonstratedthatvitaminDexerts therapeuticefects throughmultiple mechanisms including maintaining intestinal barrier，regulating immunecellsand inflammatoryfactors，modulating gut microbiota，and regulating gene expression.Clinical studies havefoundthatvitamin D supplementationcan improve UC symptoms，aleviate inflammatory response，andenhance patients’qualityof life. Additionaly，therearedifferencesinffcacieswhenvitaminDiscombinedwithdifferentdrugs.Thisarticlereviewedthe research progressonthe mechanismandsupplementationdosage ofvitamin Dinthe treatmentof UC，as wellas its role in disease assessment and clinical significance.

Key wordsColitis， Ulcerative;Vitamin D;Vitamin DReceptors；Therapy

溃疡性结肠炎（ulcerativecolitis，UC）是一种病因尚未明确、易复发的慢性非特异性炎症性肠道疾病。（剩余17644字）