硒蛋白在炎症性肠病中的作用机制

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AbstractSelenium is an essential trace element for humanbody.The primary functional form of selenium in the organism isselenoproteins (Sep),which playsacrucial rolein maintaining normal physiological functions,influencing immuneresponses,andisalsoimplicatedin tumorigenesis andrelated metabolicdisorders.Recentstudies haveshownthat Sepisinvolvedinthepathophysiological processofinflammatorybowel disease (IBD).Thisarticlereviewedthe mechanisms ofSepin IBD,aimingto explore the pathogenic mechanismsof IBDand provide insights forthe diagnosis and treatment of the disease.
Key WordsSelenium;Selenoproteins;Inflammatory Bowel Disease;Colitis-Associated Cancer;Therapy
炎症性肠病(IBD)包括克罗恩病(CD)和溃疡性结肠炎(UC),是一种慢性、进展性免疫相关疾病,目前尚无法治愈。(剩余14940字)