儿童非食管嗜酸细胞性胃肠疾病的诊治管理:欧美共识指南的解读

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Diagnosis and Treatment of Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitisin Pediatrics:Interpretationof JointEuropeanandNorthAmericanGuidelinesHE Weimei,SHAN Jiani,ZHANG Chenmei.NationalClinical Research CenterforChildHealthandDisorders&Pediatric IntensiveCare Unit,Children's Hospital,Zhejiang UniversitySchoolofMedicine,Hangzhou (310052)

Correspondence to: ZHANG Chenmei, Email: chzcm@zju.edu.cn

AbstractTheaimofthispaperistointerpret theclinical practiceguidelinesonchildhoodeosinophilic gastrointestinal disordersbeyondeosinophilicesophagitis (non-EoEEGID),jointlydevelopedbytheEuropean Societyfor Paediatric Gastroenterology,Hepatologyand Nutritionand theNorth American Societyfor Pediatric Gastroenterology, Hepatologyand Nutrition.The guidelines provide new standards for the diagnosis and treatment of non-EoE EGID.They includedetailedexplanationsondisease clasification,diagnosticand therapeuticchallenges,epidemiology,etiological mechanisms,symptoms,endoscopicand imaging examinations,othertests,diferentialdiagnosis,and treatmentstrategies. Thepaper explores the importanceofcomprehensiveassessment inchildren with non-EoEEGID.Improvementsuggestions are proposed,suchasdevelopingsymptomassessmenttools,conducting stdiesonimpactofthediseaseonqualityof life, standardizingeosinophildensityreporting,refiningdiagnosticcriteria,andformulatingspecifictreatmentguidelines.These measures aim toenhance the diagnostic and therapeutic acuracy for non-EoEEGID inpediatricsand improve the clinical management of affected children.

Key wordsChild;Non-Eosinophilic Esophagitis;Eosinophilic Gastrointestinal Disorders;Guidelines; Expert Consensus;Statement

非食管嗜酸细胞性胃肠疾病(eosinophilic gastrointestinal disordersbeyond eosinophilic esophagitisnon-EoEEGID)是一组慢性、免疫介导的胃肠道疾病。(剩余14384字)

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