基于R语言数据挖掘的外感咳嗽中药用药配伍规律研究

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【中图分类号】R254 【文献标识码】A

【Abstract】 Objective To collect and analyze outpatient prescription data for exogenous cough treatment froma hospital in Shenzhen，and to identifythe characteristics and medication paterns of traditional Chinese medicine （TCM）. Methods This study collcted prescriptions from a hospital in Shenzhen for exogenous cough treatment in January 2024.R language for data mining were used to analyze the medication frequency，clustering patterns，andassociation rules inthe treatment of exogenous cough byTCMand to explore the medication patterns and the usage of clasic formulas in TCM for this condition. Results A total of 451 outpatient prescriptions for exogenous cough were include，the top ten most frequently used herbs were Licorice， Bitteralmond，Belfower，Ephedra，Tangerne peel，Stemonaeradix，uckahoe，inelliternata，Nepetaulbof thunberg fritillary. Cluster analysis and association rules revealed that San'ao decoction， Kikyodon soup，and Zhisou powder were commonly prescribed，targeting lung function， dispersing wind，and resolving phlegm to effctively alleviatecough symptoms.Significant differences in medication usage were observed across different syndrome types.For the wind cold attacking lung pattrn，the core herbs were warm in nature and focused on dispersing with acrid-warm properties. Conversely，the treatment of wind heat attacking the lung pattern typically involved cold-natured herbs， with a primary focus on clearing and draining lung heat.Stratification by age revealed that the pediatric group often used drugs with mild properties，such as Stemona and Shegan. The young adult group tended to be prescribed cold-natured drugs like Forsythia and Hogfonnel Root. The middleaged and elderly group preferred warming and tonifying drugs such as Japanese Catnip and Perill frutescens. Conclusion The TCM treatment of exogenous cough primarily focuses on releasing the exterior and dispersing the lung. Due to the region's subtropical monsoon climate and temperature fluctuations physicians flexibly modified classical formulas such as San'ao decoction and Zhisou powder according to individual constitutions and symptom patterns.This targeted，syndrome-based approach effectively disperses the lung qi，stops cough and transforms phlegm， and alleviates cough.

【Keywords】Exogenous cough; Traditional Chinese medicine; Data mining; Medication pattern

咳嗽是以肺失宣降，肺气上逆、咯吐痰液为主的病证，有声无痰为咳，有痰无声谓嗽[]。（剩余17038字）