1例溃疡性结肠炎伴发面部无菌性脓肿患者的 药物治疗与监护

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【中图分类号】R97 【文献标识码】A

【Abstract】The clinical pharmacist was involved in the whole process of drug treatment and monitoring of a patient with ulcerative colitis （UC） and facial aseptic abscesses. After admission， clinical pharmacists and physicians jointly formulated an empirical anti-infection plan for meropenem and linezolid glucose injection. After the 5th day of medication， the patient continued to have high fever. After discusson with the physician and clinical pharmacist， it was considered that the patient's facial boil was caused by aseptic abscess syndrome，and UC with extraintestinal manifestations could not be ruled out. Hydrocortisone succinate sodium was added intravenously.

After the 9th day of treatment， the patient's facial abscesses improved.Subsequently， the physician followed the clinical pharmacist's advice and used infliximab as the subsequent treatment plan.After the 11th day of treatment，the patient's symptoms improved significantly. During the 2-month follow-up，the facial abscesses completely disappeared，the stoolwas normal，andthere were no special discomforts.The participationof clinical pharmacists in clinical practice improves patients' understanding of the disease and treatment compliance， providing patients with individualized medication support to ensure the safety and efectivenessof medication.

【Keywords】 Ulcerative colitis; Aseptic abscess; Parenteral manifestation; Infliximab; Pharmaceutical care

溃疡性结肠炎（ulcerativecolitis，UC）是炎症性肠病（inflammatoryboweldisease，IBD）的一种类型，是由遗传、环境和肠道菌群失调等因素引起的慢性且易复发的肠道非特异性炎症，临床表现为持续或反复发作的腹泻、黏液血便、腹痛及里急后重等，中、重度活动期患者可出现发热、乏力、体重下降等全身症状和肠外表现。（剩余8184字）