射血分数超常的心力衰竭的研究进展

【中图分类号】R541.62【文献标识码】A DOI：10.12114/j.issn.1007-9572.2024.0307

【Abstract】More and more studies have proved that heart failure with supra-normal ejection fraction（HFsnEF） isanewheartfailurephenotypewithdiferentcharacteristics，butitsstudyisstillintheexploratorystageathomeandbroad Thecriticalvalueofsupernomaljectionfraction（snLVEF）isstllontroversial，butmoststudiesdefineitasleftvtricular ejection fraction>65 % ；the proportion of elderly and female patientswith HFsnEFis higher，with lower natriuretic peptide valuesandsmalerleftventricles，andvalvulardisease，arhthmia，andhypertensiveheartdiseasearethemaincausesofheart failure；andtherelationshipbetween HFsnEFandmortalityhasagender-dependentnature，posiblyduetotheprevalenceof coronarymicrovasculardisorders inelderlywomen，coupledwithsmallheartsizeandhighsympatheticexcitability，making them morelikelytosuffercardiovascularevents；thecurrentdiagnosisandtreatmentofHFsnEFstllfollowstheHFpEFapproachBy combingtheliterature，thispapersystematicallydiscusss theresearchprogressofHFsnEF，withaviewtoprovidingaeference for the in-depth study of HFsnEF.

【Key Words】Heartfailure；Heartfailure with supra-normal ejectionfraction；Ejectionfraction；Sympathetic nervous system；Review

心力衰竭是不同病因引起的一组临床综合征，其病理生理机制存在差异，包含3个要素：（1）心脏结构和/或功能异常；（2）心力衰竭的症状和/或体征；（3）脑钠肽水平升高和/或肺部或全身瘀血的客观证据。（剩余13964字）