阿达木单抗长疗程治疗中重度银屑病的临床疗效及安全性分析

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【摘要】目的：研究探讨阿达木单抗长疗程治疗中重度银屑病的临床疗效及安全性。方法：将2020年1月—2021年1月在本科室接受治疗的中重度银屑病的患者18例作为本次研究的对象，分为对照组和观察组，每组9例。对照组患者给予常规治疗；观察组患者给予阿达木单抗长疗程治疗。观察对比两组患者治疗后的情况。结果：观察组患者的总有效率更佳，两组对比差异具有统计学意义（P

【关键词】阿达木；中重度银屑病；临床疗效；安全性

The Clinical Efficacy and Safety of Adalimumab Long-term Treatment in the Treatment of Moderate to Severe Psoriasis

WANG Liyan， ZHAN Xinghong

Kaiyuan people’s Hospital， Kaiyuan， Yunnan 661699， China

【Abstract】Objective：To study the clinical efficacy and safety of long-term treatment of adalimumab in the treatment of moderate to severe psoriasis. Methods：Eighteen patients with moderate to severe psoriasis who were treated in the undergraduate room from January 2020 to January 2021 were taken as the subjects of this study， and they were divided into control group and observation group， each group had 9 cases. Patients in the control group were given conventional treatment； Patients in the observation group were given adalimumab long-term treatment. The conditions of the two groups of patients after treatment were observed and compared.Results：The total effective rate of patients in the observation group was better， and the difference between the two groups was statistically significant （P

【Key？Words】Adalimumab； Moderate to severe psoriasis； Clinical efficacy； Safety

银屑病又名牛皮癣，是一种红斑鳞屑性皮肤病，银屑病临床表现以红斑、鳞屑为主，瘙痒搔抓或可出血，全身均可发病，以头皮、四肢较为常见，其病因至今尚不清楚，一部分患者有家族性发病史；某些患者患病是由上呼吸道感染引发的；某些患者免疫功能下降以后免疫反应亢进，引发银屑病。（剩余3417字）