以外周水肿及腹水为主要临床表现的POEMS综合征一例

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摘要：POEMS综合征是一种罕见的单克隆浆细胞增殖性疾病，经典五联征包括多发性周围神经病、器官肿大、内分泌病变、M蛋白血症和皮肤改变，但在实际临床工作中，其表现复杂多变，并不典型，极易造成误诊和漏诊。本文报道1例以外周水肿及腹水为主要临床表现的POEMS综合征。

关键词：POEMS综合征；水肿；腹水

中图分类号： R559  文献标志码： B  文章编号：1000-503X（2023）01-00167-04

DOI：10.3881/j.issn.1000-503X.14697

POEMS Syndrome with Peripheral Edema and Ascites as the Main Manifestations：Report of One Case

LIU Wen，ZHANG Bingqiang

Department of Gastroenterology，the First Affiliated Hospital of Chongqing Medical University，Chongqing 400016，China

Corresponding author：ZHANG Bingqiang Tel：023-89012020，E-mail：429374467@qq.com

ABSTRACT：POEMS syndrome is a rare disease caused by monoclonal plasma cell proliferative disorder.The typical signs include peripheral neuropathy，organ enlargement，endocrine disease，M proteinemia，and skin changes.In clinical practice，the atypical，complex，and changeable clinical manifestations of this syndrome can easily lead to misdiagnosis and missed diagnosis.A case of POEMS syndrome with peripheral edema and ascites as the main manifestations is reported in this paper.

Key words：POEMS syndrome；edema；ascites

Acta Acad Med Sin，2023，45（1）：167-170

POEMS综合征是一种单克隆浆细胞异常增殖性疾病，因其罕见性、多系统受累和临床高度异质性，早期诊断存在一定困难。（剩余5051字）