基于数据挖掘探讨唐宋时期治疗胸痹心痛方剂的用药规律

打开文本图片集

Analysis ofthe Medication Rules for Chest Painand Heartache in the Tang and Song Dynasties Basedon Data Mining MAO Ju， SU Chang，WAN Siyuan，YAO Chengzeng

Shuguang Hospital Afliated to Shanghai Universityof Traditional Chinese Medicine，Shanghai 201203，China Corresponding Author YAO Chengzeng，E-mail： ycz5959@126.com

AbstractObjective：ToexploretheprescriptionrulesofchestpainandheartacheinTangandSongDynasties.Methods：The representaiveprescrptionsforreatingchestpainandhartpainofthemedicaldataoftheTangandSongdynastieswerescreedand medicationpatesereanalydusingequencyaalysis，usteraalysisndssociationulealysiseuls：Teepresetatiesf theTangDastritosingeiaceteddg Licoricewerethemostfrequentlyusedingredients.Highfrequencydrugcusteranalysisshowedfourdistinctclusters，predominantly composedofwarm-naturedandtonifyingherbalsubstances.Associationruleanalysisshowed14coreherbpairs，suchasaconiteand driedginger，AsarumandDriedGinger，AngelicasinensisandGinseng，amongothers.TherepresentativeprescritionsoftheSong Dynastywerecolected.Therewere338fomulas，involving246kindsof traditionalChinesemedicines.Theherbwithhigherusage frequencywereCinnamon，Angelicasinensis，riedGngeadixucklandiendDriedangerineletc.Higfreqencydrug clusteranlysisshowedthreeclusters，mostofthemweredrugsthatwarmyangandregulatingQi.High-frequencydrugclusteranalysis showedthreelusters，mostofthemweredrugswitharmyangandregulatingQiAssociationruleanalysisidentied15coredrugpis， includingCinamonandAngelicasiensis，RedOchreandDriedGingeraswellasTichsanthesandPinellaConusionTngDyasty physiciansmadegooduseofWenyangandatachedgreatimportancetothemethodofreplenishingQiandblood，whileSongDyasty physicianspaidmoreatentiontotheregulatingQiandinvigoratingbloodonthisbasis，ndatesaetieusedwarmingmethodsto treat chest obstruction and heart pain.

Keywordschest pain; heartache; Tang and Song dynasties; data mining; medication rules

胸痹心痛是一种常见中医疾病，主要是以病人胸前区出现疼痛为临床特征，严重时其疼痛会放射至病人背部，造成其不得卧[1]，该中医病症的描述最早源于《内经》，《灵枢·本藏》白：“肺小则少饮，不病喘喝；肺大则多饮，善病胸痹、喉痹、逆气”。（剩余8553字）