睡眠障碍病人心力衰竭风险预测模型的建立与验证

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AbstractObjective：Toexplretheriskfactorsofheartfalueinpatientswithsleepdisoders，stablishingandevaluatingaNoogram modelofheartfalure.Methods：Patientswithsleepdisordersfrom2O08-2O2OwereretrievedthroughtheNationalHealthandNutrion Examination Survey，and they were divided into to training set and validation set at a ratio of 3： 1.The significant variables for establishing themodelwerescreenedusingLAsSOregresson.Themodelevaluationaccuracyanddiscriminationwereassessedusingconsistency index（C-nde）atiotceatinacteistisilis）us： patientswithsleepdisorderswereincluded.ANomogramof heartfailurewasconsructedbasedonthescreenedriskfactors（coronary heartdiseasestoyofhpertesionndochemicalidicatorsuchsboodgucosetotalcolesteroluriccidndtine）. TheC-indexofthtrainigsetas835%Cl098ndtheCdexofextealvaidatioas074695%Cl0-4e resultsofcairationplotsuggestedthatthemodelsowedgoodacuracyitnbsoluteeoofapproximately05Dcisiocue analysisindicatedthatthismodelhelddiagnosticvalueforpatientswithheartfalueConclusion：ThepreditiveNomogrammodelcould identify heart failure patientswithsleepdisorders.

Keywordsheart failure;sleep disorders; risk factors;predictive model;decision curveanalysis

2021年，美国心力衰竭协会（HeartFailureSocietyofAmerica，HFSA）明确了心力衰竭的定义，其为不同病因引起的一组临床综合征，要求具备3个要素：1）心脏的结构和功能的异常；2）心力衰竭的症状和体征；3）利钠肽水平升高和（或）肺部或全身淤血的客观证据[1]。（剩余12284字）