血清内ALT、LSR及NLR对胃肠间质瘤患者病情分级及临床预后的影响

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[摘要] 目的 探讨血清内ALT、LSR及NLR对胃肠间质瘤（GIST）病情分级及临床预后的影响。 方法 选取2016年1月至2017年12月张家港市第一人民医院收治的GIST患者82例，根据病情分级进行分组，比较不同病情分级GIST患者ALT、LSR及NLR水平，并研究各指标对患者预后的影响。 结果 中危组、高危组ALT、LSR及NLR水平均显著高于极低危组和低危组，高危组ALT、LSR及NLR水平均显著高于中危组（P

[关键词] 胃肠间质瘤;ALT;LSR;NLR;病情分级;临床预后

[中图分类号] R735.2          [文献标识码] B          [文章编号] 1673-9701（2022）04-0047-05

[Abstract] Objective To explore the influence of serum ALT， LSR and NLR on the disease grading and clinical prognosis of patients with gastrointestinal stromal tumor（GIST）. Methods Eighty-two patients with GIST in the First People′s Hospital of Zhangjiagang from January 2016 to December 2017 were selected and they were divided into different groups according to their disease grading. The ALT， LSR and NLR levels of GIST patients with different disease grading were compared， and the influence of each index on the prognosis of patients was studied. Results The levels of ALT， LSR and NLR in middle-risk group and high-risk group were significantly higher than those in extremely low-risk group and low-risk group， while the levels of ALT， LSR and NLR in high-risk group were significantly higher than those in middle-risk group （P

[Key words] Gastrointestinal stromal tumor; ALT; LSR; NLR; Disease grading; Clinical prognosis

肝脏是胃肠道间质瘤（gastrointestinal stromal tumor，GIST）的主要转移器官，而血清丙氨酸氨基转移酶（alamine aminotransferase，ALT）和天冬氨酸氨基转移酶（aspartate transaminase，AST）均是临床评估肝功能的常用指标[1]。（剩余5694字）