三氯生涂层缝合线预防成人开腹手术后感染效果的Meta分析

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Efficacy of triclosan coated sutures to prevent infection after laparotomy in adults：a Meta-analysis

LIU Ziting，XIE Yuzhen，CHEN Jinlong，ZHANG Aihua，HE Peiliang

Guangzhou Red Cross Hospital，Guangdong 510220 China

Corresponding Author ZHANG Aihua，E-mail：453469065@qq.com

Abstract Objective：To compare the effectiveness of triclosan coated and uncoated sutures in reducing surgical site infections after adult open surgery through Meta-analysis.Methods：The literature about effectiveness of triclosan coated suture in preventing postoperative infections in adults undergoing open surgery were retrieved from databases such as CNKI，WanFang Database，VIP，CBM，MedLine，EMbase，the Cochrane Library.The retrieval time was from the inception to February 16，2022.After screening according to inclusion and exclusion criteria，the data was analyzed using RevMan 5.3.Results：A total of 5 797 patients were included in 12 articles.The incidence of surgical site infection in triclosan coated and uncoated sutures was 10.4% and 13.6%，respectively，with statistically significant differences （RR=-0.03，95%CI ―0.06-―0.01，P=0.010）;three studies only involved peritonitis surgery and found that antimicrobial coated sutures had better efficacy （RR=0.37，95%CI 0.19-0.73，P=0.004）.Conclusion：Current evidence shows that triclosan coated sutures have advantages in reducing the incidence of surgical site infections in general abdominal incisions.

Keywords antibacterial suture;triclosan coated;surgical site infections;digestive surgery;Meta-analysis;evidence-based nursing

摘要 目的：通过Meta分析比较三氯生涂层与无涂层缝合线在成人开腹手术术后减少手术部位感染的有效性。（剩余12822字）