清热凉血汤联合围刺治疗银屑病的临床疗效及安全性研究
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摘 要 目的：研究分析采用清热凉血汤与围刺联合治疗银屑病患者的临床效果。方法：将银屑病患者86例随机分为对照组和观察组，各43例。对照组采用单一清热凉血汤治疗，而观察组在此基础上，加以围刺联合治疗，比较两组各项指标。结果：治疗后，观察组的治疗有效率高于对照组；四项目瘙痒量表、皮肤病生活质量指数、银屑病面积与严重性指数以及中医证候评分，转化生长因子b、肿瘤坏死因子a、白介素-23以及白介素-17水平和不良反应发生率均低于对照组（P
关键词 银屑病 围刺 清热凉血汤 炎症因子
中图分类号：R246.7； R275.9 文献标志码：A 文章编号：1006-1533（2024）17-0045-04
引用本文 王洁， 刘兴静， 曹前， 等. 清热凉血汤联合围刺治疗银屑病的临床疗效及安全性研究[J]. 上海医药， 2024， 45（17）： 45-48.
基金项目：上海市卫生健康委员会中医药科研项目（2020LP007）
Clinical efficacy and safety study of Qingre Liangxue decoction combined with encircling needling in the treatment of psoriasis
WANG Jie1， LIU Xingjing1， CAO Qian2， LI Yue1， XIA Qin3， XU Rong4
（1. Department of Traditional Chinese Medicine； 2. Department of Acupuncture and Moxibustion； 3. Department of Pharmacy， Ruijin Hospital， Shanghai Jiao Tong University School of Medicine， Shanghai 200025， China； 4. Department of Dermatology， Yueyang Hospital of Integrative Medicine， Shanghai University of Traditional Chinese Medicine， Shanghai 200437， China）
ABSTRACT Objective： To study and analyze the clinical effect of Qingre Liangxue decoction combined with encircling needling in the treatment of patients with psoriasis. Methods： Eighty-six patients with psoriasis were randomly divided into a control group and an observation group with 43 cases each. The control group was treated with a single Qingre Liangxue decoction， while the observation group was additionally treated with encircling needling， and the various indicators were compared between the two groups. Results： After treatment， the treatment effectiveness rate was higher， the four-item itch scale， dermatologic quality of life index， psoriasis area and severity index， and Chinese medicine syndrome score， transforming growth factor-b， tumor necrosis factor-a， interleukin-23 and interleukin-17 levels， and the incidence of adverse reactions were all lower in the observation group than the control group （P
KEY WORDS psoriasis； encircling needling； Qingre Liangxue decoction； inflammatory factors
银屑病是皮肤科的一种常见病、多发病，主要指的是以皮损部位毛细血管增生过度和表皮增殖过度为主要特征的一种红斑鳞屑性皮肤病，也被称之为牛皮癣，具有病程长、复发率高、反复发作的特点[1-2]。（剩余5723字）