紫杉醇复合顺铂同步放疗盆腔淋巴结阳性Ⅲ期宫颈癌的疗效

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摘 要 目的:探讨紫杉醇复合顺铂同步放疗盆腔淋巴结阳性Ⅲ期宫颈癌的治疗效果。方法:将80例盆腔淋巴结阳性Ⅲ期宫颈癌患者随机分入对照组和观察组各40例。对照组予以顺铂同步放疗治疗,观察组予以紫杉醇复合顺铂同步放疗治疗。观察两组患者的临床疗效以及发生的不良反应情况。结果:观察组患者的临床疗效,不良反应发生率,随访3年的生存、复发、转移情况优于对照组(均P

关键词 紫杉醇 顺铂 放疗 盆腔淋巴结阳性Ⅲ期宫颈癌 治疗效果

中图分类号:R979.19; R737.33 文献标志码:B 文章编号:1006-1533(2022)07-0020-02

引用本文 梁业, 陈勇, 刘小兰. 紫杉醇复合顺铂同步放疗盆腔淋巴结阳性Ⅲ期宫颈癌的疗效[J]. 上海医药, 2022, 43(7): 20-21; 71.

Efficacy of paclitaxel combined with cisplatin in concurrent radiotherapy for pelvic lymph node-positive stage Ⅲ cervical cancer

LIANG Ye, CHEN Yong, LIU Xiaolan

(Department of Oncology, Xin’gang Central Hospital, Xinyu 338000, China)

ABSTRACT Objective: To explore the effect of concurrent radiotherapy with paclitaxel and cisplatin for pelvic lymph node-positive stageⅢ cervical cancer. Methods: Eighty patients with pelvic lymph node-positive stageⅢ cervical cancer were randomly divided into a control group and an observation group with 40 cases each. The control group was treated with concurrent cisplatin radiotherapy while the observation group was treated with paclitaxel combined with cisplatin concurrent radiotherapy. The clinical efficacy and adverse reactions in the two groups were observed. Results: The clinical efficacy, incidence of adverse reactions, survival, recurrence, and metastasis at 3 years of follow-up were better in the observation group than the control group(all P

KEy wORDS paclitaxel; cisplatin; radiotherapy; pelvic lymph node-positive stageⅢcervical cancer; therapeutic effect

宫颈癌属于临床常见的妇科恶性肿瘤,患者初期一般无明显临床症状,随着疾病的进展,可表现为阴道异常出血、接触性出血等,而在疾病晚期,肿瘤会侵犯宫颈周围组织或器官,则会出现肛门坠胀感、腿部肿胀、肾功能损伤、阴道大出血等临床现象,严重威胁着患者的生命安全[1]。(剩余2856字)

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