射频消融术联合臭氧在腰椎间盘突出症患者中的应用效果分析

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摘 要 目的：探讨射频消融术联合臭氧在腰椎间盘突出症患者中的应用效果。方法：将80例腰椎间盘突出症患者随机分为射频消融术组（n=40，等离子射频消融术）和联合治疗组（n=40，等离子射频消融术+臭氧治疗），对比两组疗效、腰椎功能和疼痛改善情况，以及血清炎性因子水平。结果：联合治疗组治疗总有效率显著高于射频消融术组；两组治疗后各时间点日本骨科协会评估治疗分数（Japanese Orthopaedic Association scores， JOA）、视觉模拟评分（visual analogue scale， VAS）、白介素-6（interleukin-6， IL-6）和IL-8水平均较治疗前改善，且术后各时间点联合治疗组JOA、VAS评分优于射频消融术组，IL-6、IL-8下降水平显著低于射频消融术组（均P

关键词 腰椎间盘突出症 射频消融术 臭氧 腰椎功能

中图分类号：R681.57 文献标志码：B 文章编号：1006-1533（2022）05-0046-04

引用本文 钱游伷， 蔡舒婷. 射频消融术联合臭氧在腰椎间盘突出症患者中的应用效果分析[J]. 上海医药， 2022， 43（5）： 46-49.

Analysis of the effect of radiofrequency ablation combined with ozone in patients with lumbar disc herniation

QIAN Youyou， CAI Shuting

（Department of Pain， the First Hospital of Sanming City， Fujian Medical University， Sanming 365000， China）

ABSTRACT Objective： To investigate the effect of radiofrequency ablation combined with ozone in patients with lumbar disc herniation. Methods： Eighty patients with lumbar disc herniation were randomly divided into a radiofrequency ablation group （n=40， underwent plasma radiofrequency ablation） and a combined treatment group （n=40， underwent plasma radiofrequency ablation plus ozone）. The curative effect， lumbar function， pain improvement and serum inflammatory factors levels were compared between the two groups. Results： The overall response rate was significantly higher in the combined treatment group than the radiofrequency ablation group. The Japanese Orthopaedic Association score （JOA）， visual analogue scale（VAS）， the levels of interleukin-6 （IL-6） and IL-8 in the two groups were all improved at various time points after treatment， and furthermore the improvement of JOA and VAS and the decrease of IL-6 and IL-8 levels were more significant in the combined treatment group than the radiofrequency ablation group （all P

KEy WORDS lumbar disc herniation； radiofrequency ablation； ozone； lumbar spine function

随着社会的发展和人们生活方式的改变，腰间盘突出症的患病率逐年上升。（剩余4633字）