液体活检在肺癌早期诊断中的应用研究进展

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[摘要]液体活检是肺癌诊断的一种重要方法,较之传统组织活检,有安全无创、标本易获取、可动态监测等优势,在早期肺癌诊断中有确切价值。本文总结国内外液体活检诊断早期肺癌的研究进展,探讨其在早期肺癌诊断中的价值。
[关键词]液体活组织检查;肺肿瘤;早期诊断;生物标记,肿瘤;综述
[中图分类号]R734.2;R446.8[文献标志码]A[文章编号]2096-5532(2024)03-0470-05
doi:10.11712/jms.2096-5532.2024.60.106[开放科学(资源服务)标识码(OSID)]
[网络出版]https://link.cnki.net/urlid/37.1517.R.20240730.1145.003;2024-07-3109:16:33
Research advances in the application of liquid biopsy in the diagnosis of early-stage lung cancerHUANG Tongtong, XIN Ying, YIN Xiaojiao, SUN Yanqiu, XU Tao(Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Qing-dao University, Qingdao 266000, China)
[Abstract]Liquid biopsy is an important method for the diagnosis of lung cancer, and compared with traditional tissue biopsy, liquid biopsy has the advantages of favorable safety, noninvasiveness, convenience in obtaining specimens, and dynamic monitoring. Therefore, it has a marked value in the diagnosis of early-stage lung cancer. This article summarizes the research advances in liquid biopsy in the diagnosis of early-stage lung cancer in China and globally and discusses its value in the diagnosis of early-stage lung cancer.
[Key words]liquid biopsy; lung neoplasms; early diagnosis; biomarkers, tumor; review
肺癌是世界范围内发病率及病死率最高的恶性肿瘤之一, 据美国癌症协会统计,2020年全球肺癌新增病例和新增死亡病例在所有癌症中的占比分别是11.4%和18.0%[1]。(剩余13515字)