三种常见制粒技术对中药制剂内在质量的影响及生产过程控制要点

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【摘 要】 比较分析湿法挤出制粒、干法制粒、流化床制粒3种不同制粒方式对中药制剂的内在质量的影响，根据其制粒方式浅论生产过程质量控制要点，为中药生产企业制粒方式的选择提供参考。

【关键词】 干法制粒；湿法挤出制粒；流化床制粒；中药颗粒；质量

【中图分类号】R944   【文献标志码】 A    【文章编号】1007-8517（2024）15-0054-04

DOI：10.3969/j.issn.1007-8517.2024.15.zgmzmjyyzz202414013

The Influence of Three Common Granulation Techniques on The Intrinsic Quality of Traditional

Chinese Medicine Preparations and The Control Points of Production Process

Abstract：The influence of three different pelleting methods which are extrusion granulation of wet，dry granulation and fluidized bed granulation on the quality of traditional Chinese medicine preparations was compared and analyzed.The main points of quality control in the production process were discussed according to the pelleting methods，which could provide reference for the selection of pelleting methods in Chinese medicine manufacturers.

Key-words：Dry Granulation; Granulation of Wet; Fluidized Bed Granulation; Traditional Chinese Medicine Granules; Quality

制粒是多种固体制剂的基础操作单元，在中成药中也较为常见。（剩余8300字）