胰腺疾病相关消化不良的诊治

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摘要： 各类胰腺疾病均可能引起消化不良，其主要机制在于胰腺实质损伤和/或胰管阻塞导致胰腺外分泌功能不全，消化功能受损，进而引发营养不良、体质量下降和预期生存期缩短等严重临床后果。因此，临床上应对胰腺疾病相关消化不良予以足够重视，提高其诊断及治疗率，以改善胰腺疾病患者的生活质量，延长总体生存期。

关键词： 胰腺疾病； 消化不良； 胰腺外分泌功能不全

基金项目： 国家自然科学基金面上项目（82273426）； 上海市卫生健康委员会科研项目计划书（202240380）

The diagnosis and treatment of pancreatic disease-related dyspepsia

WANG Xiaoyi， FU Deliang

Department of Pancreatic Surgery， Huashan Hospital， Fudan University， Shanghai 200040， China）

Corresponding author： FU Deliang， surgeonfu@163.com （ORCID： 0000-0003-1832-2000）

Abstract： Various pancreatic diseases can cause dyspepsia due to pancreatic exocrine insufficiency （PEI） caused by pancreatic parenchymal injury and/or pancreatic duct obstruction， which further leads to impaired digestive function and a series of severe clinical outcomes such as malnutrition， weight loss， and shortened survival time. Therefore， pancreatic disease-related dyspepsia should be taken seriously in clinical practice to improve its diagnosis and treatment rates， so as to improve the quality of life of patients with pancreatic diseases and prolong overall survival time.

Key words： Pancreatic Diseases； Dyspepsia； Exocrine Pancreatic Insufficiency

Research funding： General Program of National Natural Science Foundation of China （82273426）； General Program of Shanghai Municipal Health Commission （202240380）

胰腺是仅次于肝脏的人体第二大外分泌器官，兼具有内、外分泌两大功能［1］。（剩余10234字）