细胞器之间相互作用在非酒精性脂肪性肝病发生发展中的作用

打开文本图片集
摘要:细胞器除了具有各自特定的功能外,还可与其他细胞器相互作用完成重要的生理功能。细胞器之间相互作用的异常与疾病的发生发展密切相关。近年来,细胞器之间相互作用在非酒精性脂肪性肝病(NAFLD)发生发展中的作用受到关注,特别是线粒体、脂滴与其他细胞器之间的相互作用。
关键词:非酒精性脂肪性肝病; 细胞器; 线粒体; 脂肪滴
基金项目:国家自然科学基金面上项目(82070618)
Role of organelle interaction in the development and progression of nonalcoholic fatty liver disease
LIU Tianhui. (Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China)
Corresponding author: LIU Tianhui, liu_tianhui@163.com (ORCID:0000-0001-6789-3016)
Abstract:In addition to its own specific functions, an organelle can also interact with other organelles to complete important physiological functions. The disorders of organelle interactions are closely associated the development and progression of various diseases. In recent years, the role of organelle interactions has attracted more attention in the progression of nonalcoholic fatty liver disease, especially the interactions between mitochondria, lipid droplets, and other organelles.
Key words:Non-alcoholic Fatty Liver Disease; Organelles; Mitochondria; Lipid Droplets
Research funding:National Natural Science Foundation of China(82070618)
细胞器可以通过膜接触位点与其他细胞器相互作用,完成物质与信息的交换,形成互作网络[1]。(剩余15770字)