川崎病423例临床特征分析

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Clinical characteristics analysisof 423 cases with Kawasaki disease Fu Minghong，Huang Huiyi， Huang Fengling.Department ofPediatric Cardiology，Quanzhou Women'sandChildren's Hospital，Quanzhou Children's Hospital Fujian ，China

【Abstract】ObjectiveTo investigate and analyze the clinical features of Kawasaki Disease（KD）.Methods Atotalof 423 children with Kawasaki disease who were hospitalized inour hospital from January 2018 to December 2O2O wereselectedas thestudyobjects.Clinicaldataofallchildren were investigated，and C-reactive protein（CRP）andserum procalcitonin （PCT） were detected.The levelsof PCT，D dimer，high-density lipoprotein and serum albumin were analyzed.ResultsAmong the423children，according to theclinical diagnostic criteria， they were divided into a complete group：252 cases with complete Kawasaki disease，accounting for 59.6% ，and anincomplete group：171 cases with incomplete Kawasaki disease，accounting for 39.4% .Theclinical symptoms （neck lymph nodeenlargement，hand-footdisease，conjunctival congestion，oral disease，rash），cardiovascularand nervous system complications and treatment outcomes were statistically significant between the complete group and the incomplete group（ P <0.05）. The white blood cell count，platelet count，haemoglobin and erythrocyte sedimentation rate in the complete group werenot significantly different from those in the incomplete group（ P> （20 0.05）.The levels of serum CRP，PCT and D-dimer in the complete group were higher than those in the incomplete group （ P <0.05），and the contents of high-density lipoprotein and serum albumin in the complete group were lower than those in the incomplete group（ P <0.05）.Logistic regression equation analysis showed that serum CRP，PCT，Ddimer，high-density lipoproteinandserumalbumin levelswereall influential factors leading to the occurrence of complete Kawasaki disease （P

【Key Words】Kawasaki disease;Clinical features；C-reactive protein；Procalcitoni；D dimer;High density lipoprotein;Serum albumin

川崎病（Kawasakidisease，KD）是一种儿童期特有的全身性血管炎症性疾病，又称皮肤黏膜淋巴结综合 征（mucocutaneous lymph node syndrome，MCLS）主要影响中小动脉，尤其是冠状动脉，引发急性发热和多种皮肤黏膜表现1]。（剩余7513字）