冥想改善轻度认知障碍的临床与机制研究进展

摘要：轻度认知障碍（MCI）易进展为痴呆，目前尚无理想的干预方法。近年来的研究显示，冥想具有改善大脑认知功能的潜力，且其成本低廉、安全性高，已被推荐用于诸多神经精神疾病的康复领域。本文从冥想的概念背景、临床疗效、作用机制等角度综述其在MCI治疗方面的运用与前景，以期为后续的临床研究和应用提供参考。

关键词：冥想；轻度认知障碍；认知功能

中图分类号： R749.1 文献标识码： A 文章编号：1000-503X（2024）02-0260-07

DOI：10.3881/j.issn.1000-503X.15602

Clinical and Mechanism Research Progress in Amelioration of Mild Cognitive Impairment via Meditation

SHEN Xiaoyan1，PU Zhengping1，2

1Department of Psychogeriatrics，Affiliated Mental Health Center of Jiaxing University（Kangci Hospital of Jiaxing），Jiaxing，Zhejiang 314500，China

2Shanghai Key laboratory of Psychotic Disorders，Shanghai Mental Health Center，Shanghai Jiao Tong University School of Medicine，Shanghai 201108，China

Corresponding author：PU Zhengping Tel：0573-88083919，E-mail：rabbitpzp@139.com

ABSTRACT：Mild cognitive impairment（MCI）has a high risk of progressing to dementia，with no recommended therapies.Recent studies have shown that meditation has huge potential to improve the cognitive function，with low cost and high safety，being suitable to be applied in the treatment of neurological and psychotic disorders.This paper reviews the application and prospects of meditation in treating MCI from the concept，clinical efficacy，and mechanism of meditation，aiming to provide reference for future clinical studies.

Key words：meditation；mild cognitive impairment；cognitive function

Acta Acad Med Sin，2024，46（2）：260-266

轻度认知障碍（mild cognitive impairment，MCI）指记忆力或其他认知功能进行性减退，但不影响日常生活能力，且未达到痴呆的诊断标准，其涉及注意力、执行功能、语言功能、记忆学习能力、视空间功能等认知功能域中的一项或多项受损［1］。（剩余18845字）