诱导多能干细胞的研究进展

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【摘要】 对诱导多能干细胞(induced pluripotent stem cell,iPSC)的应用研究从2006年开始已经逐渐成为干细胞研究和临床治疗领域的一个热门课题。这项技术的问世为再生医学、疾病建模和医药发展提供了前所未有的机会。本文就iPSC的发展前景和相关应用进行综述。

【关键词】 诱导多能干细胞 疾病模型 再生医学 遗传安全性

Research Progress of Induced Pluripotent Stem Cell/JIANG Yuxiao, YU Hao. //Medical Innovation of China, 2023, 20(20): -188

[Abstract] The application of induced pluripotent stem cell (iPSC) has gradually become a hot topic in the field of stem cell research and clinical treatment since 2006. The advent of this technology offers unprecedented opportunities for regenerative medicine, disease modeling and pharmaceutical development. This paper reviews the development prospect and related applications of iPSC.

[Key words] Induced pluripotent stem cell Disease model Regenerative medicine Genetic safety

First-author's address: Clinical Medicine Major of Capital Medical University Eighth Clinical School, Beijing 100038, China

doi:10.3969/j.issn.1674-4985.2023.20.042

1981年,研究人员首次从鼠胚胎中提取出一种能不断增殖并能充分发育的小鼠胚胎干细胞(mESCs)。(剩余9174字)

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