慢性阻塞性肺疾病合并肺癌体液中的潜在生物标志物研究进展

【摘要】 慢性阻塞性肺疾病（COPD）并发肺癌患者的数量与日俱增，并且COPD合并肺癌的患者相较于普通肺癌患者往往具有更明显的临床症状及更差的预后。因此，基于人体尿液、痰液、唾液、支气管肺泡灌洗液等体液，寻找一种新的生物标志物实现COPD合并肺癌的早诊、早治十分重要。

【关键词】 肺癌 COPD 生物标志物 体液

Research Progress of Potential Biomarkers in Body Fluids of Patients with Chronic Obstructive Pulmonary Disease Complicated with Lung Cancer/CHEN Guoqing， MA Hongxia. //Medical Innovation of China， 2023， 20（10）： -165

[Abstract] The number of patients with chronic obstructive pulmonary disease （COPD） complicated with lung cancer is increasing day by day， and patients with COPD complicated with lung cancer often have more obvious clinical symptoms and worse prognosis than ordinary lung cancer patients. Therefore， based on human urine， sputum， saliva， bronchoalveolar lavage fluid and other body fluids， it is very important to find a new biomarker to realize the early diagnosis and treatment of COPD complicated with lung cancer.

[Key words] Lung cancer COPD Biomarkers Body fluids

First-author's address： The Fourth Clinical College of Xinjiang Medical University， Urumqi 830000， China

doi：10.3969/j.issn.1674-4985.2023.10.038

慢性阻塞性肺疾病（COPD）是一种以持续性气道气流受限为特征的呼吸系统疾病。（剩余10706字）