幽门螺杆菌感染与结直肠息肉相关性的研究进展

摘要 幽门螺杆菌（Hp）感染在全球普遍流行，是WHO公布的Ⅰ类致癌原。结直肠息肉可分为非腺瘤性和腺瘤性，后者是公认的结直肠癌癌前病变。越来越多的研究发现Hp感染与结直肠息肉的形成存在一定的关联。本文就Hp感染与结直肠息肉相关性的研究进展作一综述，从而为临床胃肠道疾病诊治策略的制订提供参考。

关键词 幽门螺杆菌； 结直肠息肉； 结直肠肿瘤

Progress of Research on Correlation Between Helicobacter pylori Infection and Colorectal Polyps DING Zhuyun， YAN Huihui， CAI Jianting. Department of Gastroenterology， the Second Affiliated Hospital， Zhejiang University School of Medicine， Hangzhou （310009）

Correspondence to： CAI Jianting， Email： jtcai6757@zju.edu.cn

Abstract Helicobacter pylori （Hp） infection is widely prevalent in the world and is a Group Ⅰ carcinogen announced by WHO. Colorectal polyps can be classified as non⁃adenomatous polyps and adenomatous polyps， and adenomatous polyps is recognized as precancerous lesion of colorectal cancer. More and more studies have found that Hp infection is associated with the formation of colorectal polyps. This article reviewed the progress of research on correlation between Hp infection and colorectal polyps， so as to provide reference for the formulation of clinical diagnosis and treatment strategies for gastrointestinal diseases.

Key words Helicobacter pylori; Colorectal Polyps; Colorectal Neoplasms

幽门螺杆菌（Helicobacter pylori， Hp）是一种有鞭毛的螺旋形微需氧革兰阴性杆菌，于1983年由澳大利亚学者在人类胃黏膜活检标本中首次分离并成功培养[1]。（剩余15261字）