静动脉二氧化碳分压差在重型颅脑创伤患者治疗中的应用

【摘要】重型颅脑创伤（sTBI）作为临床常见的危重症，发病率逐年上升，且sTBI患者常预后不佳。近年的研究发现，静动脉二氧化碳分压差（Pcv-aCO2）对患者早期病情评估、指导调整治疗方案、预测疾病结局等方面有较好的临床应用价值。本文对近年来Pcv-aCO2在sTBI治疗中的应用进行综述。

【关键词】重型颅脑创伤；二氧化碳分压差；微循环；心肌损伤

【中图分类号】R651【文献标志码】A【文章编号】1672-7770（2023）03-0354-04

Research progress in guiding the clinical treatment of severe traumatic brain injury with central venous-to-arterial carbon dioxide partial pressure difference LI Minghao， BI Liqing， QUE Jun. Nanjing Medical University， Nanjing 210029， China

Corresponding author： QUE Jun

Abstract： The severe traumatic brain injury is critical with increasing incidence yearly. Patients with sTBI often have poor prognosis. Recent studies have found that central venous-to-arterial carbon dioxide partial pressure difference（Pcv-aCO2） has good clinical application value for assessment of patients' early condition， adjustment of treatment plan and predicting prognosis. This paper reviews the application of Pcv-aCO2 in the treatment of sTBI.

Key words： severe traumatic brain injury; Pcv-aCO2; microcirculation; myocardium injury

颅脑创伤指因暴力直接或间接作用于头部引起的头皮、软组织、颅骨及颅脑组织的损伤，其中格拉斯哥评分3～8分、昏迷时间＞6 h的患者被诊断为重型颅脑创伤（severe traumatic brain injury，sTBI）。（剩余10127字）