产褥期颅内静脉血栓形成的危险因素分析

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Doi：10.3969/j.issn.1673—5293.2025.12.015

[中图分类号]R173 [文献标识码]A [文章编号]1673—5293（2025）12—0098-05

Analysis risk factors for cerebral venous thrombosis in the postpartum period

SHEN Shiqi，YE Yangzi，PENG Leixuan，LI Xuelan （ ， ， 71oo61，）

[Abstract]ObjectiveToanalyzetheclinicaldata patients withpostpartumcerebralvenous thrombosis（CVT）toexplorethe relatedriskfactorsforCVTduringthepuerperumbasedoncurentprevious evidence.MethodsAtotal8puerperalpatients diagnosed with CVT in the Afiliated Xi′ an from July 2010 to January 2O24 were included. Generalclinicalinformation，linicalmanifestations，laboratoryimagingfindings，treatmentstrategies，prognosiswere collected retrospectively analyzed. Results mean age the 8 patients was （26.5±4.6） years， the average hospital stay was 19.1±5.9 ）days.Allpatients presented with headacheas the initial symptom.One patient had a history gestational hypertension，onehadanupperrespiratorytractinfectiontwoweekspriortwohadahistoryhyperthyroidism.All8patients showed elevated D-dimer levels;fibrin degradation products were increased in 6 patients （ 87.5% ）;fibrinogen was elevated in 3 patients （37.5% ）;hemoglobin levels were reduced in 5 patients 62.5% ）.Homocysteine levels were tested in 6 patients，among whom5 83.3% ）were elevated.Imaging examinations revealed cortical venous thrombosis in 1 case （12.5% ） venous sinus thrombosis in 7 cases （87.5% ），involving the superior sagittal sinus in 6 cases （75.0% ），transverse sinus in 5 cases （62.5%） ， sigmoid sinusin 5 cases（ 62.5% ）， straight sinus in 2 cases （25.0%）.Six cases （ 75.0% ）involved ⩾2 venous sinuses.All patients receivedlow-molecular-weight heparinanticoagulationdehydrationtherapytoreduce intracranial pressreAmong the8 patients，6（ 75.0% ） had afavorable prognosis.Conclusion Genetic coagulation abnormalities，infections，elevated homocysteine， comorbidities such as hyperthyroidism hypertension are important risk factors for postpartum CVT.

[Keywords] puerperium;cerebral venous thrombosis;risk factor;prognosis

颅内静脉血栓形成（cerebral venousthrombo-sis，CVT）是一种由各种病因诱发的脑血管疾病，其主要表现为血液回流受阻或者脑脊液循环出现问题，从而引发颅内高压和局部脑损伤，这种疾病在所有脑血管疾病中的比例大约为 0.5%～1.0%[1] 。（剩余8420字）