超声引导下人工腹水辅助兔肝出血模型建立的实验研究

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ABSTRACTObjectiveTo exploretheapplication value ultrasound-guidedartificial ascites injection in assisting theestablishmentactiveliverhemorhagemodelsinrabbits.MethodsAtotal2Oadultmalerabbitsweredividedntothe artificial ascites-asisted group（GroupA）andthedirectpuncture group（GroupB），with10rabbits ineach group.In GroupA， artificialasciteswasinjectedunderultrasound-guided，andtheactiveliverhemorrhagemodelsinabbitswereconstructedby percutaneous punctureand cuting the liver.In Group B，the active liver hemorrhage models inrabbits were established by directpercutaneous punctureandcutting theliverunderultrasound-guided.High-frame-ratecontrast-enhanced ultrasound wasused toobserveandcomparethediferences inthenumberactive bleedingpoints，thebleedingvisualizationtime，and theshape bleeding trajectoriesbetween thetwo groups.ResultsGroupAexhibited 63active bleeding pointsandbleeding visualizationtime51.0O（40.00，80.0O）s，whileGroupBexhibited28activebleeding pointsandbleeding visualizationtime 38.00（31.25，46.75）s，with statistically significant diferences（both P<0.05 ）.Additionally，there were significant differences in the proportions bundle-shaped，fountain-shaped，anddot-shaped bleeding lesionsbetween the twogroups（all P<0.05 ） ConclusionEstablishment liverhemorhage models inrabbitsasstedbyultrasound-guidedartificial ascites injectioncan improve the visualization eficiencyactive bleeding，providinganew methodfortheestablishment animal models liver hemorrhage.

KEYWORDsUltrasound-guided;Artificial ascites;Contrastagent;Liver hemorrhage;Animal model，rabbits

腹部外伤中，肝外伤的发生率占 15%～20%[1] ，而严重肝外伤的死亡率高达 26%[2] ，故肝活动性出血的快速诊断与有效处理是临床急诊创伤救治的关键。（剩余6155字）