【摘要】 目的 评估我院口服降糖药的应用状况，为临床合理用药提供参考。方法 采用限定日剂量分析方法，统计我院2005~2007年口服降糖药的用药频度(DDDs)、购药金额、每日药费(DDC)等数据。结果 口服降糖药的DDDs逐年增长，购药金额略有增长，DDDs排名前4位的是二甲双胍、阿卡波糖、瑞格列奈、吡格列酮；购药金额始终排名第1位的是阿卡波糖。购药金额序号与DDDs序号比值在0．25~4之间。结论 阿卡波糖、二甲双胍、瑞格列奈、吡格列酮在我院口服降糖药使用中占主导地位，尤其新品种在我院得到了广泛的应用。我院口服降糖药的使用基本合理。
【关键词】口服降糖药；用药频度；药物应用分析
Analysis on use of oral hypoglycemic drugs in our hospital from 2005 to 2007
LIU Yu-qin.Peking University Shenzhen Hospital，Shenzhen 518036，China
【Abstract】 Objective To evaluate the use of oral hypoglycemic drugs in our hospital in order to provide an reference for rational use of drugs in clinic.Methods DDDs,sales volume,and daily expenses of drugs in our hospital from 2005 to 2007 were analyzed with the method of DDD analysis.Results DDDs of oral hypoglycemic drugs increased year by year,sales volumes increased slightly.The top 4 oral hypoglycemic drugs in respect of DDDs were Metformin,Acarbose,Repaglinide,Pioglitazone; The top oral hypoglycemic drug in respect of sales volume was Acarbose continuosly; The ratio of sales volume sequencing to that of DDDs was between 0．25-4.Conclusion Acarbose,Metformin，Repaglinide and Pioglitazone were mostused in our hospital,especially the new hypoglucemic drugs were widely used.The use of oral hypoglycemic drugs in our hospital is rational in the main.
【Key words】Oralhypoglycemicdrugs;DDDs; Analysis of drug use
糖尿病是患者数目逐年上升的、严重危害人类健康的一种疾病，合理应用降血糖药物，能较好地控制血糖，减少慢性并发症的发生，提高改善生活质量。（剩余2559字）