[摘要] 目的：了解肝硬化病因构成比的逐年变化趋势，间接推断接种乙肝疫苗对肝硬化病因构成的影响。方法：回顾性分析180例肝硬化住院患者的病因、并发症及Child-Pugh分级的情况。结果：病因构成中，乙型病毒性肝炎后肝硬化99例（55.00%），酒精性肝硬化38例（21.11%），乙型病毒性肝炎合并酒精性肝硬化24例（13.33%）。不同病因肝硬化的并发症中，上消化道出血81例(46.0%)，感染52例(29.6%)，肝功能分级B级90例（50.0%）。结论：病毒性肝炎（主要为乙肝）仍是我国肝硬化的最主要的病因，而酒精性和乙肝合并酒精性肝硬化的发病率呈上升趋势。肝硬化患者的并发症仍以上消化道出血为主，其次为感染，住院患者的肝功能多为B级。
[关键词] 肝硬化；病因；并发症
[中图分类号]R575.1 [文献标识码] B[文章编号] 1673-7210（2009）02（a）-129-03
Study of etiology and complications in 180 cases of liver cirrhosis
TAN Ying，TAN Qing-hua*, ZHOU Li
(Department of Gastroenterology, Affiliated Hospital of Guiyang Medical University，Guiyang 550004,China)
[Abstract] Objective: To analyze constituent ratio of etiology and complications of liver cirrhosis. Methods: 180 inpatients with liver cirrhosis were investigated retrospectively in causes, complication and Child-Pugh classification retrospectively．Results: 99(55.00%)cases were caused by the infection of hepatitis B virus．Alcohol was accounted for 38 cases(21.11%)． Two factors(hepatitis B virus and alcoho1)existed in 24(13.33%)patients．Upper gastrointestinal hemorrhage occurred in 81(46.0%) cases, 52(29.6%) patients complicated the infection. 90(50.0%) cases were classified to B in Child-Pugh Classification. Conclusion: It is suggested that hepatitis B virus is still the major cause of liver cirrhosis in GuiZhou．Cirrhosis caused by alcohol and two factors(hepatitis B virus and alcohol) reveals a tendency of increase．Upper gastrointestinal hemorrhage is still the main complication in liver cirrhosis, and the second is infection. The liver functions are mostly classified to stage B in Child-Pugh Classification.
[Key words] Cirrhosis; Etiology; Complication
肝硬化是由各种不同的原因引起的常见的弥漫性肝病，其病因很多，在我国以病毒性肝炎最常见，在西方则以酒精中毒多见[1]。（剩余1436字）