文章编号：1004-9231(2008)08-0372-04
摘要：[目的] 探讨浦东新区手足口病的流行病学和病原学特征。 [方法] 使用国家疾病监测信息管理系统开展手足口病监测，并对部分病例进行病原体检测。 [结果] 手足口病是浦东新区儿童中发病率较高的一种传染病，2~5岁组儿童发病率达1 000/10 万以上，男性多于女性，5—7月为发病高峰季节，在托幼机构易引起爆发。采集疱疹液43 份，经RT-PCR 检验，17 份为肠道病毒71 型( EV 71) 阳性，阳性率为39.53 %，4份为柯萨奇病毒A16型(CoxA16)阳性，阳性率为9.3%。 [结论] 手足口病的发生有明显年龄、性别、季节差异，EV71 是近年来引起儿童手足口病的主要病原体，开展手足口病流行病学和病原学研究，将有助于提出更好的预防和控制措施。
关键词：手足口病；流行病学；病原学 中图分类号：R 183 文献标识码：A
Surveillance and analysis of hand-foot-mouth disease in Pudong New Area 2005-2007 ZHU Wei-ping，CHU Qiang，WANG Yong，SHEN Yi-feng (Pudong District Center for Disease Control and Prevention，Shanghai 200136，China)
Abstract：[Objective] To find out the epidemiological characteristics and the important pathogens of hand-foot-mouth disease (HFMD). [Methods] Surveillance and report was done according to national disease supervision information management system of hand-foot-mouth disease. Some patients were diagnosed through RT-PCR. [Results] It was found that hand-foot-mouth disease was one of the infectious diseases with high incidence in Children. The incidence of children aged 2 to 5 exceeded 10/1000 and outbreaks used to occur at nurseries and kindergartens，with obvious peak season in summer. The incidence differed between male and female. The positive rate of EV71 was 39.53 % (17/43) ，The positive rate of CoxA16 was 9.30 % (4/43). [Conclusion] Incidence differs between sexes，seasons and ages. The important pathogen of HFMD is EV71. To study the epidemiological characteristics and etiology of hand-foot-mouth disease helps to suggest better control and prevention it in future .
Key words：Hand-foot-mouth disease；Epidemiologys；Etiology
手足口病是儿童的一种常见传染病，易在幼托机构出现集聚性发病，严重影响儿童的身体健康。（剩余1192字）